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SCS RESEARCH PROJECTS
PRESENT SCS PROJECTS
Spinal Cord Society Research Center
(projects include bridging, delivery systems, transplants,
regeneration, and scar disruption.)
Estimated annual cost:         $800,000 - $1,000,000
Reports on various Center projects appear in the SCS Newsletter each month.
MILESTONES TO CURE
BEFORE 1940--A severe spinal injury was nearly always an immediate death sentence.
1940       Antibiotics and modern rehab enable most patients to live but not be cured.
1950s      Drugs and oxygen first used to reverse paralysis in a few new injuries.
1960s      Late decompressions begin although first done in 1930's.
1968       First spinal cord cooling operation (hypothermia) done on a new injury.
1976       Clinical applications of hypothermia on new injuries in Canada.
1978       SCS founded. Newsletters announce the need for centralized research
              and treatment.
1979       First SCS research grant made.
1980       First SCS Chapters.
1981       First SCS Cure Research Conference.
1982       FES computerized walking first brought to the forefront by SCS grants.
1982       First SCS National Convention. Researchers say CNS regeneration now feasible.
1982       SCS computerized Data and Referral System begun.
1983       First artificial spinal bone substitute research funded by SCS.
1983       First targeted regeneration research begun by SCS.
1984       President Reagan commends SCS activities in his State of the Union Address on
              national TV.
1984       First chronic Spinal Cord Center started at the University of Minnesota by SCS.
1985       First inhibitor control and antiserum research--SCS project.
1986       First axonal regeneration via applied electric fields--SCS project.
1987       First artificial restoration of spinal cord function--SCS project.
1987       SCS-sponsored Center for Paralysis Research at Purdue University.
1988       First RES dog trials in the CPR at Purdue.
1989       Human trials with 4-AP.
1990       Humanization of RES.
1990       Scar neutralization at UAB.
1991       Clinical trials with beta agonist-FES therapy, University of Minnesota.
1991       Gene therapy at last, Colorado State University.
1991       Scar disruption and axonal regeneration on bridges at UAB.
1992       Precision delivery of treatments via liposomes, University of Alaska, Anchorage.
1993       Development of neuroliposomes, UAA.
1993       Refunction begins with scar disrupter, UAB.
1993       First new neuron trials, CSU.
1994       Immunoliposome clinical trials in gene therapy, CSU.
1994       Refunction trials with scar disrupter plus combinations, UAB.
1995       Trials with portable miniaturized extremity pump, Marquette University.
1995       Clinical trials with combinations of growth factors, scar disrupter, bridges, new
              neurons, and inhibitor controls: CSU, UAB, UTM, UAA, and UV.
1996-97   Combination trials in regeneration and refunction, UAB.
1997-98   Analyses of proliferation and differentiation of human CNS neurons and stem
              cells, Cedars-Sinai Medical Center, Los Angeles, CA.
1997-98   Prevention of UTI using E. coli bacterial interference, Baylor.
1998       New method for relief of persistent pain resulting from chronic spinal cord injury, U of M.
1998       Stem cell human trials announced by Cedars-Sinai.
1999       Neurotrophin method of blocking all inhibitors found at Hunter College.
1999       Neural stem cells changed to other types of cells simply by changing their enviroment
              rather than them, National Neurological Institute, Milan, Italy.
1999-01   Spinal cord restoration by combining exercise with growth factors, UCLA and UAB.
2000       Successful Parkinsonism human trial with SCS research support, Cedars-Sinai Medical
              Center in Los Angeles. Later Quashed
2001       Spinal Cord Society cure Research Center opens.
2002       New Center research program.
2002       First nasal glial cell human trials in Portugal and Australia.
2002       SCS Research Center fully staffed.
2002       SCS Center research seeking means to improve the resulting refunction from human
              olfactory cell (nasal cell) and bone cell (stromal cells) transplant trials.
2003       Human trials planned.
2005       U.S. SCS -- SCS Canada. Human trials planned at the University of Alberta, Edmonton.
2007       Chronic scar ablation succeeds.
2008       First chronic refunction produced.
2009       30% refunction now in chronic animals
2009       Human Trials?
2010       TANES restores locomotion in chronic, complete injury in rats.
2011       Electrophysiology project in chronic, complete laboratory rats.
SCS plans to continue it's efforts to increase public awareness of potential progress in this crucial field, and to focus research and advanced treatment in a centralized program for cure.
RACKET WATCH
Warning: Spinal Cord Society is the incorporated name of SCS in the U.S. as well as SCS Canada in Canada. Others using our name or attempting to raise funds using it do not represent SCS.
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